UPT™ is Shantani's proprietary technology that helps identify the targets without derivatization of the test molecule.
[Low False Positive Identifications]
This method relies on a validated hypothesis that weak-molecular interaction forces of a drug-like molecule can be utilized in preparing their affinity matrix, without any derivatization of the compound. Though interactions are weak in nature, the sum of multiple weak interactions will allow the molecule to stay on a surface, that provides complementary interactions, for a time that is sufficient for it to further interact with its affinity protein partners in a biological sample. Thus prepared affinity matrix then can be used to enrich the target protein from biological sources.